December 10, 2019
Engineered T cells have been used to treat cancer, autoimmune diseases and infections. These cells are altered to express chimeric antigen receptors (CARs) that combine an antigen recognition domain with intracellular T cell signaling components which directs T cell specificity and functionality
Know MoreDecember 02, 2019
When Jonathan Epstein first looked through the microscope to examine the results of a study using CAR T cells in mice, he didn’t know whether the sample came from a treated animal or a control
Know MoreNovember 29, 2019
We participated into China Cell/Immuno Therapy Conference in Bejing on December 29-November 1, 2019. The pioneers in this field attended this event.
Know MoreDecember 02, 2019
An immunotherapy drug that could save some cancer patients from the ordeal of extreme chemotherapy may also help them live longer, researchers say.
Know MoreNovember 07, 2019
Refractory or relapsed B lymphoblastic leukemia (B-ALL) patients have a dismal outcome with current therapy. We treated 42 primary refractory/hematological relapsed (R/R) and 9 refractory minimal residual disease by flow cytometry (FCM-MRD + ) B-ALL
Know MoreNovember 07, 2019
Cecilia Barron feels for one of the two bumps on her scalp. “Here it is,” she says, gently touching a spot on the top of her head. It’s invisible, unless Barron parts her hair to reveal the little nodule, a lump of flesh no bigger than a pea. In an hour, a nurse will come into the room, feel for the bumps, and slide a needle into each one, plunging millions of cells into Barron’s head
Know MoreOctober 29, 2019
The first CAR T cell therapy targeting the B cell-activating factor receptor on cancerous cells eradicated CD19-targeted therapy-resistant human leukemia and lymphoma
Know MoreAug 10, 2019
Less than five years ago, Chinese healthcare was a closed-off, low-quality system where the richest left the country for medicines and treatments, and the poorest took a bad diagnosis as a death sentence.
Know MoreAug 02, 2019
In tumor cell immunity, T cells play a central regulatory role. T cells are divided into several major subsets based on different
Know MoreAug 02, 2019
A Chinese company has presented early clinical data on two CAR-T therapies in patients with kidney cancer
Know MoreAug 02, 2019
Novel immunotherapeutic agents targeting tumor-site microenvironment are revolutionizing cancer therapy. Chimeric antigen receptor (CAR)-engineered
Know MoreAug 02, 2019
Timunity therapeutics is a biotech start-up company coming out of UPenn, with a cutting-edge technology in immunotherapy, it has recently attracted 135 million in funding for Series A. The start-up
Know MoreMarch 12, 2018
On March 12, 2018 the Chinese FDA (CFDA) approved the clinical trial application of LCAR-B38M CAR-T cell self-reinfusion preparation from Nanjing
Know MoreMarch 12, 2018
Researchers from the Office of Clinical Evaluation of Biological Products, Center for Drug Evaluation, China Food and Drug Administration recently produced
Know MoreMarch 24, 2019
In China, a patient whose life was close to its end was completely cured of leukemia by stimulating the immune system using CAR T-cell therapy
Know MoreMarch 24, 2019
HANGZHOU, China, May 6, 2016 /PRNewswire/ -- At the 2016 Haematogenic Immunity Summit held in Hangzhou from April 22 to 24, 2016
Know MoreMarch 24, 2019
Before (left) and after (right) PET scans of a patient with multiple myeloma treated with BCMA-targeted CAR T cells.
Know MoreMarch 24, 2019
Cellular therapies are a rapidly evolving approach to myeloma treatment, which bring a unique mechanism of action with the potential to overcome drug resistance and induce long-term remissions.
Know MoreMarch 24, 2019
The burgeoning pipeline of chimeric antigen receptor (CAR) T-cell therapies targeting B-cell maturation antigen (BCMA)
Know MoreMarch 24, 2019
Chimeric antigen receptor (CAR) gene therapy is a breakthrough technology in treating refractory hematologic malignancies
Know MoreMarch 24, 2019
an advance in the groundbreaking cancer treatment known as CAR T-cell therapy appears to eliminate its severe side effects
Know MoreMarch 24, 2019
A phase I study out of China has provided additional evidence that chimeric antigen receptor (CAR) T-cell therapy targeting B-cell maturation antigen (BCMA) leads to deep and durable responses in some patients
Know MoreMay 21 2018
The Health Research Council (HRC) of New Zealand and the National Natural Science Foundation of China (NSFC) have announced a joint funding initiative to support further
Know MoreMay 21 2018
Instead of getting chemotherapy or waiting for hematopoietic stem cell transplantation, a 12-year-old girl from southwest China's Chongqing Municipality was saved by a non-conventional therapy
Know MoreJune 14 2018
Insights into CAR-T cell therapy presented at the 23rd Congress of the European Haematology Association, 14–17 June 2018, Stockholm
Know MoreJune 14 2018
LAKEWOOD, Colo., USA--October 9, 2018-- UniCAR-Therapy Bio-Medicine Technology Co. chose Terumo BCT and its cell expansion devices to automate its cell therapy
Know MoreJune 14 2018
Policy of CAR-T therapy in China 1.The declaration of CAR-T treatment in China has been accepted
Know MoreJune 14 2018
A Chinese CAR-T therapy that drew significant attention at last year’s American Society of Clinical Oncology meeting will enter a clinical trial in the US later this year.
Know MoreDecember 3, 2018
With regulatory approval of Chimeric Antigen Receptor (CAR) T-cell therapies for treating patients with aggressive blood cancer
Know More16 July 2019
Division of Hematology, Center for Cell Therapy and Regenerative Medicine, Antwerp University Hospital, Antwerp, Belgium 2Laboratory of Experimental Hematology
Know More16 July 2019
In China, a patient whose life was close to its end was completely cured of leukemia by stimulating the immune system using CAR T-cell therapy
Know More16 July 2019
Each of the many BCMA-targeted chimeric antigen receptor (CAR) T cells in development demonstrate a different efficacy and safety profile,
Know More16 July 2019
A novel approach to CAR-T cancer therapy promises to upend what has become a truism in medicine: that the treatment’s dramatic effect on tumors comes
Know MoreJuly 29, 2018
The options available to cancer patients are changing rapidly thanks to developments in our understanding of the interplay between cancer and the immune system
Know MoreJuly 29, 2018
Results from two early-phase clinical trials suggest that a form of immunotherapy that uses genetically engineered immune cells may be highly effective
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