CAR T-Cell Therapy for Lymphoma

Indication: B-cell Lymphoma 

Therapy: CAR-T treatment

Inclusion & exclusion criteria:

Inclusion Criteria:

1. Patients with CD19+ B-cell Lymphoma(At least 2 prior combination chemotherapy regimens)

2. To be aged 3 to 75 years

3. ECOG score ≤2

4. Women of childbearing potential must have a urine pregnancy test taken and proven negative prior to the treatment. All patients agree to use reliable methods of contraception during the trial period and until follow-up for the last time.

Exclusion Criteria:

1. Intracranial hypertension or unconsciousness

2. Respiratory failure

3. Disseminated intravascular coagulation

4. Hematosepsis or Uncontrolled active infection

5. Uncontrolled diabetes

Attention: 

This criteria is only for your reference, the final decision should be done by the hematologist in the hospitals.

CR Rate:  CD19 70%

Time frame:

1. Examination & test: one week

2. Pre-treatment & T-Cell Collection: one week

3. T-Cell preparation & return: two-three weeks

4. 1st Effectiveness analysis: three weeks

5. 2nd Effectiveness analysis: three weeks